Ian Book delivered the type of clutch, game-winning drive that can make Notre Dame fans forgive the quarterback\u2019s mistakes. Book ran 7 yards for a touchdown with 29 seconds left to cap an 18-play, 87-yard drive as the 16th-ranked Fighting Irish pulled out a 21-20 victory over visiting Virginia Tech and averted a second straight loss. After being blown out 45-14 at Michigan last week, Notre Dame faced some harsh criticism. \u201cThis week was about our team,\u201d Book said after his designed run on 3rd-and-goal tied the game at 20-20. \u201cIt was about having that strong love for each other and just going out there for one another and playing for each other.\u201d Jonathan Doerer kicked the go-ahead PAT after holder Jay Bramblett fielded a low snap and freshman Kyle Hamilton then picked off a long pass by Quincy Patterson to seal the victory, the 16th straight by the Irish in Notre Dame Stadium. \u201cThat was a great character victory for our football team,\u201d Irish coach Brian Kelly said. \u201cThey endured a lot this week. They found a way to win.\u201d Book led a methodical drive, converting two fourth downs, including a 4th-and-10 at the Tech 33 for 26 yards to Chase Claypool that gave the Irish 1st-and-goal from the 7. After two incomplete passes, Notre Dame caught Virginia Tech in a blitz and Book ran away from it and darted into the end zone. \u201cJust a lot of grit and perseverance,\u201d Notre Dame tight end Cole Kmet said. Book passed for 341 yards, with two touchdowns and two interceptions, and led the Irish with 50 yards on 13 carries. The Irish committed three turnovers deep in Hokies territory, including a fumble at the goal line by Jafar Armstrong that Hokies safety Divine Deablo returned for a 98-yard TD to tie the game at 14 with 9 seconds left in the first half. The Hokies (5-3) added a pair of field goals by Brian Johnson in the second half and the Irish missed one, leaving Notre Dame trailing by six with 3:19 remaining and the ball at its 13. But Book and the Irish came through. #4 Clemson 59, Wofford 14: Trevor Lawrence scored four touchdowns, Travis Etienne ran for 212 yards and two TDs and the host Tigers (9-0) won their 24th consecutive game, rolling over the FCS\u2019 Terriers (5-3). Etienne, the reigning ACC player of the year, had scoring runs of 47 and 86 yards in the first 15:12. Clemson improved to 34-0 against FCS programs. It was the Tigers\u2019 sixth straight win over Wofford (5-3), which fell to 1-21 against FBS schools. Etienne became Clemson\u2019s first rusher with three 200-yard games in his career. He also surpassed James Davis for Clemson\u2019s career record for rushing TDs with 48. #11 Auburn 20, Mississippi 14: Bo Nix passed for a career-high 340 yards and had a 1-yard touchdown as the host Tigers (7-2, 4-2 SEC) mostly dominated on the stat sheet but struggled to put the 19-point underdogs away after repeated stalled drives and three missed field goals. Anders Carlson\u2019s third miss, a 47-yarder with 1:14 to play, gave Ole Miss (3-6, 2-4) a shot at a winning drive. The Rebels, who had no timeouts left, quickly moved from their 31 into Auburn territory. John Rhys Plumlee hit Braylon Sanders for an 18-yard pass and then ran 20 yards. Finally, on 4th-and-3 from the 35, Plumlee scrambled around and made a desperation heave under pressure. Christian Tutt intercepted the ball and raced most of the way to the other end zone. And Auburn, which was coming off a 23-20 loss at No. 1 LSU, managed to survive. Nix completed 30 of 44 passes, including a 78-yarder to Harold Joiner that set up Auburn\u2019s first touchdown. Fellow freshman D.J. Williams got most of his 24 carries and 93 yards in the second half. Anthony Schwartz gained 89 yards on nine catches, including a 50-yarder. #14 Michigan 38, Maryland 7: Giles Jackson returned the opening kickoff 97 yards for a touchdown and the visiting Wolverines (7-2, 4-2 Big Ten) used two first-half scoring runs by freshman Zach Charbonnet to pull away from the Terrapins (3-6, 1-5). Jackson\u2019s game-opening dash down the right sideline set the tone. Charbonnet ended Michigan\u2019s first drive with a 2-yard run, and the defense made those two scores stand up. The Wolverines\u2019 special teams contributed, too. In addition to the kickoff return, Michigan used a successful fake punt to set up Charbonnet\u2019s second TD, and a partially blocked punt led to a third-quarter touchdown run by Hassan Haskins for a 35-0 lead. Javon Leake\u2019s 97-yard kickoff return in the third quarter was one of few highlights for the Terrapins. #17 Cincinnati 46, E. Carolina 43: Sam Crosa kicked a 32-yard field goal as time expired to lift the visiting East Division-leading Bearcats (7-1, 4-0 American Athletic Conference). Desmond Ridder threw for 161 yards and a touchdown, rushed for 146 more and led the winning drive in the final 1:10 for the 24\u00bd-point favorites, who trailed by 12 points with less than 9 minutes left before escaping with their sixth win in a row. Ahmad Gardner returned an interception 62 yards for a touchdown with 4:38 remaining to give Cincinnati a short-lived 43-40 lead, and Michael Warren II rushed for 141 yards and three touchdowns. Holton Ahlers threw for a school-record 535 yards, matched a career high with four touchdown passes and rushed for a score for the Pirates (3-6, 0-5). Jake Verity tied it at 43 with his third field goal, a 27-yarder with 1:14 remaining \u2014 plenty of time for Ridder and the Bearcats to rally. #22 Kansas St. 38, Kansas 10: Skylar Thompson ran for 127 yards and three touchdowns, Harry Trotter added 92 yards rushing and another score and the visiting Wildcats (6-2, 3-2) showed no letdown from their upset of then-No. 5 Oklahoma in bludgeoning the Jayhawks (3-6, 1-5) for the 12th consecutive time. #23 Wake Forest 44, N.C. State 10: Jamie Newman returned from injury to throw for three touchdowns and run for two more for the Demon Deacons (7-1, 3-1 ACC), who got off to a dominating start that had this one wrapped up early. #24 Memphis 54, #15 SMU 48: Brady White threw for 350 yards and three touchdowns, Antonio Gibson had a school-record 386 all-purpose yards with three scores and host Memphis held off SMU to cap the biggest day in the Tigers\u2019 football history. The Tigers (8-1, 4-1) handed SMU its first loss of the season and moved atop the American Athletic Conference\u2019s Western Division to improve their case to represent the Group of Five in the New Year\u2019s Six. SMU (8-1, 4-1) came in with its best start to a season since 1982, when the Mustangs won their first 10 games. They left having lost their sixth straight in Memphis in a series dominated by the Tigers. Community colleges CCSF 40, Chabot 7: Demonte Aleem made his first start for the visiting Rams and rushed for 176 yards and a touchdown on 16 carries. CCSF (6-2, 2-1 NorCal Bay 6) gained 500 yards of total offense, including 280 on the ground. Ethan Bullock completed 14 of 20 passes for 176 yards and two touchdowns in 2\u00bd quarters of play. Jacob Cruz came in and completed 5 of 6 passes for 39 yards. Kenden Robinson Jr. caught five passes for 101 yards. Chabot (4-3, 1-1) was intercepted four times by CCSF, twice by Timote Finau.